Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2077 |
Adavosertib
AZD1775,MK-1775,Adavosertib (MK-1775) |
Wee1 | Cell Cycle/Checkpoint |
Adavosertib (MK-1775) 是一种Wee1抑制剂,IC50值为 5.2 nM。它阻碍了 G2 DNA 损伤检查点。 | |||
T71067 | MK-1775 hemihydrate | ||
MK-1775 hemihydrate is a WEE1 inhibitor with potential antineoplastic sensitizing activity. | |||
T71065 |
Quinapril-d5
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Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con... |