Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1999 |
MEN 11270
|
||
Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3); conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5). |