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Cat. No. Product Name Target Signaling Pathways
T17873 (4R,5S)-nutlin carboxylic acid

E3 ligase Ligand 15,MDM2 ligand 2

Others Others
(4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].
T18632 PROTAC MDM2 Degrader-2

Others; PROTACs Others; PROTAC
PROTAC MDM2 Degrader-2 is a compound designed utilizing PROTAC technology, functioning as a MDM2 degrader. Comprised of a highly potent inhibitor targeting MDM2, a linker, and the MDM2 ligand for E3 ubiquitin ligase, this compound facilitates the degradation of MDM2[1].
T18609 PROTAC ERRα Degrader-2

Others Others
PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group. This compound is designed to specifically degrade estrogen-related receptor alpha (ERRα), acting as an ERRα degrader[1].
T18055 K-Ras ligand-Linker Conjugate 2

Others Others
K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].

化合物

(4R,5S)-nutlin carboxylic acid
Cat.No: T17873
Synonym: E3 ligase Ligand 15,MDM2 ligand 2
Target: Others
PROTAC MDM2 Degrader-2
Cat.No: T18632
Synonym:
Target: Others, PROTACs
PROTAC ERRα Degrader-2
Cat.No: T18609
Synonym:
Target: Others
K-Ras ligand-Linker Conjugate 2
Cat.No: T18055
Synonym:
Target: Others
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