Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17902 |
Nutlin-C1-amido-PEG4-C2-N3
E3 ligase Ligand-Linker Conjugates 48,MDM2 Ligand-Linker Conjugates 1 |
Others | Others |
Nutlin-C1-amido-PEG4-C2-N3 is a novel compound that functions as a ligand-linker conjugate for the E3 ligase. It is a synthesized molecule incorporating the MDM2 ligand derived from Nutlin 3, and a 4-unit PEG linker. This compound is specifically designed for utilization in PROTAC technology. | |||
T17941 |
ERRα Ligand-Linker Conjugates 1
|
Others | Others |
ERRα Ligand-Linker Conjugates 1 refers to a chemical compound that consists of a ligand targeting estrogen-related receptor alpha (ERRα), and a PROTAC linker that facilitates the recruitment of E3 ligases MDM2. It finds utility in the synthesis of a range of PROTACs, including one known as PROTAC ERRalpha Degrader-1. With its capability to induce degradation of ERRα, PROTAC ERRalpha Degrader-1 functions as an ERRα degrader[1]. |