Cat. No. | Product Name | Target | Signaling Pathways |
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T16013 | MAT2A inhibitor 1 | Others | Others |
MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM). | |||
T60668 |
MAT2A inhibitor 3
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MAT2A inhibitor 3 可用于癌症研究。它是一种甲硫氨酸腺苷转移酶 2A (MAT2A)的抑制剂,IC50值为 <200 nM。。 | |||
T78946 | MAT2A-IN-10 | Methionine Adenosyltransferase (MAT) | Chromatin/Epigenetic |
MAT2A-IN-10(Compound 28),一种口服活性MAT2A抑制剂,其IC50值为26 nM,适用于癌症研究。 | |||
T60903 |
MAT2A-IN-4
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MAT2A-IN-4 是一种能够用于癌症研究的,甲硫氨酸腺苷转移酶 2A (MAT2A)的抑制剂。 | |||
T61243 |
MAT2A-IN-5
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MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative activity of MTAP-deficient cancer cells, MAT2A-IN-5 exhibits potential in cancer research applications [1]. | |||
T61672 | MAT2A-IN-7 | ||
MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effectively reduces the proliferative activity specifically in MTAP-deficient cancer cells, thus highlighting its potential for cancer research applications [1]. | |||
T79350 |
MAT2A-IN-12
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Methionine Adenosyltransferase (MAT) | Chromatin/Epigenetic |
MAT2A Allosteric inhibitor 2是一种有效的、选择性MAT2A变构抑制剂,具有5 nM的IC50值。在增殖试验(MTAP-/-细胞系)中,MAT2A Allosteric inhibitor 2表现出纳摩尔级别的活性,IC50为5 μM。 | |||
T63975 |
MAT2A-IN-1
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MAT2A-IN-1 是 MAT2A 的有效抑制剂,能够 MTAP 缺陷型癌细胞的增殖活性。其中 MAT2A 在几种类型肿瘤中表达水平异常高,包括胃癌、结肠癌、肝癌和胰腺癌。MAT2A-IN-1 对癌症疾病表现出研究潜力。 | |||
T79349 |
MAT2A-IN-11
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Methionine Adenosyltransferase (MAT) | Chromatin/Epigenetic |
MAT2A Allosteric Inhibitor 1 (compound 5)为针对Methionine Adenosyltransferase (MAT)的MAT2A亚型特异性抑制剂,其半抑制浓度(IC50)为6.8 nM。 |