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Cat. No.	Product Name	Target	Signaling Pathways
T61321	MAO-B-IN-12
	MAO-B-IN-12 (Compound 16c) is a highly effective inhibitor of monoamine oxidase B (MAO-B), displaying significant potency with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-12 exhibits notable neuroprotective activity [1].
T60381	LSD1-IN-12
	LSD1-IN-12 (compound 2) 是有效的 LSD1抑制剂，Ki 值分别为 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), 和 3.5 μM (MAO-B)。
T62262	Neuroinflammatory-IN-2
	Neuroinflammatory-IN-2 (compound 7i) 是一种有效的抗神经炎症剂，能够作用于 MAO-B (IC50: 10.30 μM)。Neuroinflammatory-IN-2 具有抗神经炎症活性、抗氧化活性、生物金属螯合能力和适当的血脑屏障通透性 (BBB)。Neuroinflammatory-IN-2 在 25 μM 的浓度下可以抑制 96.33% 的 Aβ1-42 聚集。Neuroinflammatory-IN-2 在 H2O2 诱导的 PC-12 细胞损伤中表现出神经保护活性。Neuroinflammatory-IN-2 能够用于研究阿尔兹海默症。
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...