Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1991L |
M 1145 acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
M1145 acetate 是一种嵌合肽,是一种选择性甘丙肽受体 2 (GAL2) 激动剂,Ki 为 6.55 nM。它对 GAL2 的亲和力比 GAL1 高 90 倍以上(Ki=587 nM),比 GalR3 的亲和力高 76 倍(Ki=497 nM)。 它对甘丙肽的信号转导具有累加作用。 | |||
TP1991 |
M1145
M 1145 |
||
Potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). Has an additive effect on the signal transduction of galanin. |