Cat. No. | Product Name | Target | Signaling Pathways |
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T71941 |
Lig3
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Lig3 is an inhibitor against high-risk strains of human papillomavirus (HPV) E6 oncoprotein. | |||
T70622 |
Selonsertib HCl
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Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby preventing its phosphorylation and activation. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis ... |