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Cat. No. | Product Name | Target | Signaling Pathways |
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T80235 |
YFLLRNP
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YFLLRNP 是 PAR-1 部分激动剂,具有生物活性。它在低浓度下选择性地激活 G12/13 信号通路,而不会对 Gq 或 Gi 通路产生影响(60 μM)。 | |||
T80236 |
TFLLRN-NH2
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TFLLRN-NH2 为具备生物活性的肽类化合物,作用为PAR-1激动剂。 | |||
T80239 |
TFLLRNPNDK-NH2
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Thrombin | Proteases/Proteasome |
TFLLRNPNDK-NH2 是具备生物活性的肽类化合物,作为凝血酶受体激活肽(PAR-1 激动剂肽)能够可逆地与 PAR-1 结合,模拟凝血酶对底物蛋白通过水解作用产生的“束缚配体”。同凝血酶的作用相似,此肽能够增加液体与蛋白质的渗透性。 | |||
T78545 |
FLLRN
TRAP-6 (2-6) |
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FLLRN是一种具有生物活性的(PAR1特异性拮抗肽)。 | |||
T70610 |
ALRN-6924
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ALRN-6924 is a novel dual MDM4 and MDM2 inhibitor. |
Cat. No. | Product Name | Species | Expression System |
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TMPK-01030 |
LRRN1 Protein, Mouse, Recombinant (His)
Neuronal leucine-rich repeat protein 1,LRN,NLRR1,NL... |
Mouse | HEK293 Cells |
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation. |