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Cat. No. Product Name Target Signaling Pathways
T70134 L-778123 Dihydrochloride

L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed.
T70133 BAY-846

BAY-846 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.

化合物

L-778123 Dihydrochloride
Cat.No: T70134
Synonym:
Target:
BAY-846
Cat.No: T70133
Synonym:
Target:
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