Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38411 |
KRA-533
|
||
KRA-533, a potent KRAS agonist, directly targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage. This inhibition leads to the buildup of constitutively active GTP-bound KRAS, which subsequently activates both apoptotic and autophagic cell death pathways specifically in cancer cells. |