Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11747 |
KD-3010
|
PPAR | DNA Damage/DNA Repair; Metabolism |
KD-3010(Kalypsys) 是一种具有口服活性有效性和选择性的 PPARδ 激动剂,可用于研究肝损伤。 | |||
T68302 |
KD3010 tosylate
|
||
KD-3010 is a peroxisome proliferator-activated receptor delta agonist potentially for the treatment of diabetes and obesity. KD-3010 dramatically ameliorates liver injury induced by carbon tetrachloride (CCl(4)) injections. Deposition of extracellular matrix proteins was lower in the KD3010-treated group than in the vehicle- or GW501516-treated group. Interestingly, profibrogenic connective tissue growth factor was induced significantly by GW501516, but not by KD-3010, following CCl(4) treatmen... |