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Cat. No. Product Name Target Signaling Pathways
T18061 KB02-SLF

Others; PROTACs Others; PROTAC
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of protein degradation in biological systems. The compound SLF acts as a linker, binding to the ubiquitin E3 ligase ligand KB02, resulting in the formation of KB02-SLF[1].

化合物

KB02-SLF
Cat.No: T18061
Synonym:
Target: Others, PROTACs
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