Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27708 |
K-14585
|
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K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8. |