Cat. No. | Product Name | Target | Signaling Pathways |
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T70065 |
JNJ-61803534
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JNJ-61803534 是一种有效的、具有口服活性 RORγt 反向激动剂,IC50为 9.6 nM。JNJ-61803534 具有抗炎活性。JNJ-61803534 在 Th17 分化条件下抑制人 CD4+ T 细胞产生 IL-17A。 | |||
T70064 |
PDE1-IN-1
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PDE1-IN-1can enhance levels of the second messengers cAMP/cGMP leading to the expression of neuronal plasticity-related genes, neurotrophic factors, and neuroprotective molecules. These neuronal plasticity enhancement properties make PDE1 inhibitors good candidates as therapeutic agents in many neurological conditions. |