Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T25522 |
Ici 216140
m216140,Ici216140,m 216140,Ici-216140,m-216140 |
Others | Others |
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated increases in blood pressure in rat |