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Cat. No. Product Name Species Expression System
TMPY-02240 STAT1 Protein, Human, Recombinant (His & GST)

IMD31A,IMD31B,IMD31C,STAT91,CANDF...

Human Baculovirus Insect Cells
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),...
TMPU-00003 STAT2 Protein, Human, Recombinant (His)

Human E. coli
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of...

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STAT1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02240
Species: Human
Expression System: Baculovirus Insect Cells
STAT2 Protein, Human, Recombinant (His)
Cat.No: TMPU-00003
Species: Human
Expression System: E. coli
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