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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62685 | IMP2-IN-2 | ||
IMP2-IN-2 是一种有效的、选择性的 IMP2 抑制剂,抑制 IMP2 与 RNA_A 和 RNA_B 相互作用的 IC50 值分别为 120.9 μM 和 236.7 μM。IMP2-IN-2 能够用于研究癌症。 | |||
T61946 | IMP2-IN-1 | ||
IMP2-IN-1 (compound 4) 是有效的IMP2抑制剂,对 IMP2 RNA 的IC50为 81.3-127.5 μM。IMP2-IN-1 降低 SW480 细胞中 IMP2 水平。IMP2-IN-1 显著抑制分化和未分化 Huh7 细胞的活力。 | |||
T61326 |
AIMP2-DX2-IN-1
|
Others | Others |
AIMP2-DX2-IN-1 是一种有效的 AIMP2-DX2 抑制剂,具有潜在的抗肿瘤活性,可用于研究淋巴癌。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01762 |
IGF2BP-2 Protein, Human, Recombinant (His & GST)
insulin-like growth factor 2 mRNA binding protein <... |
Human | Baculovirus Insect Cells |
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa c... | |||
TMPJ-00345 |
IGF2BP-2 Protein, Human, Recombinant (His)
IGF-II mRNA-Binding Protein 2,IGF2 mRNA-Bi... |
Human | E. coli |
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replicat... | |||
TMPJ-00660 |
IMPase2 Protein, Human, Recombinant (His)
Inositol-1(or 4)-Monophosphatase 2,IMPA |
Human | E. coli |
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphat... | |||
TMPH-00927 |
AIMP2 Protein, Human, Recombinant (His)
Protein JTV-1,Aminoacyl tRNA synthase complex-interacting mu... |
Human | E. coli |
AIMP2 Protein, Human, Recombinant (His) is expressed in E. coli. |