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Cat. No. Product Name Target Signaling Pathways
T3162 IDE1

Others Others
IDE1 是定形内胚层诱导物,有用于器官移植等方面的潜力。
T62836 Hit 1

Hit 1 是一种胰岛素降解酶 (IDE) 的激活剂 (EC50: 5.5 μM),能够降低刺激葡萄糖的胰岛素分泌。
T35802 ML-345

Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin action in diabetes pathogenesis, IDE plays a role in Varicella-Zoster virus infection and degradation of amyloid-β, a peptide implicated in Alzheimer's disease. ML-345 is a small molecule inhibitor that selectively targets cysteine819 in IDE with an EC50 value of 188 nM. [2] It de...

化合物

IDE1
Cat.No: T3162
Synonym:
Target: Others
Hit 1
Cat.No: T62836
Synonym:
Target:
ML-345
Cat.No: T35802
Synonym:
Target:
TargetMol Loading
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