Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19360 |
Hydroxy bosentan
Ro 48-5033 |
Others | Others |
Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Hydroxy bosentan assists BOS pharmacologically, retaining 10%-20% activities. | |||
T11584 |
Hydroxy desmethyl Bosentan
Ro 64-1056 |
Others | Others |
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver. |