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Cat. No. Product Name Target Signaling Pathways
TP1174 Endothelin-2 (49-69), human

Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2

Others Others
Endothelin-2 (49-69), human (Human endothelin-2) 是一种由 21 个氨基酸组成的血管活性肽。它可与 G 蛋白连接的跨膜受体,ET-RA 和ET-RB 结合。
TP2143 Endothelin-2 (49-69), human TFA

Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA

Others Others
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
T9621 N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonamide

Others Others
N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Met 抑制内皮素与CHO 细胞膜上人ETA 受体和人ETB 受体的的结合,IC50分别为268nM 和 1810nM。
T36007 Nebentan

Nebentan (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2]. Nebentan inhibits the specific binding of [125I] endothelin-1 to endothelin ETA and ETB receptors in a concentration dep...
T76305 [Ala2] Endothelin-3, human

[Ala2] Endothelin-3, human 为ET-3的线性类似物,其结构中的Cys残基被Ala所替代。ET-3是由人体横纹肌肉瘤细胞系产生,且仅在此细胞系中表达的一种具有血管活性的肽。在非肌肉来源的肉瘤细胞系中不表达。该肽能够作为旁分泌因子,促进内皮细胞迁移。
T73877 BQ-123 TFA

BQ-123 TFA 是一种高效、选择性内皮素 A(ETA)受体拮抗剂,IC50值为 7.3 nM,Ki 值为 25 nM。BQ-123 TFA 抑制内皮素-1 介导的人肺动脉平滑肌细胞增殖,降低高血压大鼠血压。

化合物

Endothelin-2 (49-69), human
Cat.No: TP1174
Synonym: Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2
Target: Others
Endothelin-2 (49-69), human TFA
Cat.No: TP2143
Synonym: Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA
Target: Others
N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonamide
Cat.No: T9621
Synonym:
Target: Others
Nebentan
Cat.No: T36007
Synonym:
Target:
[Ala2] Endothelin-3, human
Cat.No: T76305
Synonym:
Target:
BQ-123 TFA
Cat.No: T73877
Synonym:
Target:
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