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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77188 | Tifcemalimab | ||
Tifcemalimab (JS004) 是一种人源化抗 BTLA(B 和 T 淋巴细胞衰减因子) 单克隆抗体。Tifcemalimab 通过与 BTLA 结合,阻断 HVEM-BTLA 的相互作用,从而阻断BTLA 介导的抑制信号通路。Tifcemalimab 可用于癌症的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01750 |
HVEM Protein, Human, Recombinant (His)
HVEA,TR2,HVEM,ATAR,tumor necrosis factor receptor s... |
Human | HEK293 Cells |
HVEM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R052. | |||
TMPY-05512 |
HVEM Protein, Mouse, Recombinant (His)
Atar,Hvem,Tnfrs14,HveA,tumor necrosis factor recept... |
Mouse | HEK293 Cells |
HVEM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.8 kDa and the accession number is Q80WM9. | |||
TMPY-01425 |
HVEM Protein, Mouse, Recombinant (His & hFc)
HveA,Tnfrs14,Hvem,Atar,tumor necrosis factor recept... |
Mouse | HEK293 Cells |
HVEM Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80WM9. | |||
TMPY-05515 |
HVEM Protein, Human, Recombinant (His), Biotinylated
tumor necrosis factor receptor superfamily, member 14,CD270,... |
Human | HEK293 Cells |
HVEM Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R052. | |||
TMPY-05380 |
HVEM Protein, Human, Recombinant (hFc)
TR2,CD270,tumor necrosis factor receptor superfamily, member... |
Human | HEK293 Cells |
HVEM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.2 kDa and the accession number is A0A024R052. | |||
TMPY-05417 |
HVEM Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD270,LIGHTR,HVEA,TR2,ATAR,HVEM,tumor necrosis fact... |
Human | HEK293 Cells |
HVEM Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 46 kDa and the accession number is A0A024R052. | |||
TMPY-06941 |
HVEM Protein, Human, Recombinant (His & Avi), Biotinylated
HVEA,tumor necrosis factor receptor superfamily, member 14,C... |
Human | HEK293 Cells |
HVEM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.6 kDa and the accession number is NP_003811.2. | |||
TMPJ-00168 |
HVEM Protein, Mouse, Recombinant (hFc)
Tnfrsf14,Herpesvirus entry mediator,ATAR,Tumor necrosis fact... |
Mouse | HEK293 Cells |
Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in ... | |||
TMPJ-00620 |
HVEM Protein, Rhesus macaque, Recombinant (His)
TNFRSF14,HVEA,Tumor Necrosis Factor Receptor Superfamily Mem... |
Rhesus | HEK293 Cells |
HVEM Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-40 KDa and the accession number is F7GSW4. | |||
TMPJ-01416 |
HVEM Protein, Rhesus macaque, Recombinant (hFc)
CD270,TNFRSF14,TR2,Herpesvirus Entry Mediator A,Tumor Necros... |
Rhesus | HEK293 Cells |
HVEM Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A0A2K5W0R1. | |||
TMPK-00130 |
LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)
TNFSF14, TR2,CD258,LTg,LIGHT,HVEM-L |
Human | HEK293 Cells |
LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. | |||
TMPY-06771 |
LIGHT/TNFSF14 Protein, Mouse, Recombinant (hFc)
LIGHT,Ly113,HVEM-L,HVEML,LTg,tumor necrosi... |
Mouse | Baculovirus Insect Cells |
LIGHT/TNFSF14 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 45.09 kDa and the accession number is NP_062291.1. | |||
TMPY-04253 |
HVEM Protein, Cynomolgus, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 14 |
Cynomolgus | HEK293 Cells |
HVEM Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.2 kDa and the accession number is XP_005545061.1. | |||
TMPY-05293 |
HVEM Protein, Cynomolgus, Recombinant (His)
tumor necrosis factor receptor superfamily, member 14 |
Cynomolgus | Baculovirus Insect Cells |
HVEM Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.6 kDa and the accession number is A0A2K5W0R1. | |||
TMPY-04843 |
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His)
LTg,LIGHT,tumor necrosis factor (ligand) superfamily, member... |
Mouse | Baculovirus Insect Cells |
LIGHT/TNFSF14 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is A0A0U5JAA8. | |||
TMPY-02153 |
TNF beta Protein, Human, Recombinant
LT,TNF β,TNFSF1,肿瘤坏死因子,TNFB,lymphotoxin alpha,lymphotoxin α |
Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRS... | |||
TMPH-01620 |
TNF beta Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. | |||
TMPJ-00129 |
BTLA Protein, Human, Recombinant (His)
B- and T-Lymphocyte-Associated Protein,CD272,BTLA,B- and T-L... |
Human | HEK293 Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ... | |||
TMPH-02770 |
TNF beta Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. TNF beta Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.8 kDa and the accession number is P09225. |