Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02217 |
HSC70 Protein, Human, Recombinant (His)
HSP73,HSC54,HSP71,NIP71,LAP-1,HEL-33,HSPA10,HSC... |
Human | E. coli |
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 belongs to the heat-shock cognate subgroup. Members of the human heat-shock protein multigene family have several highly conserved proteins with structural and functional properties in common but vary in the extent ... | |||
TMPJ-00717 |
BAG2 Protein, Human, Recombinant (His)
BAG-2,BAG Family Molecular Chaperone Regulator 2,BAG2,Bcl-2-... |
Human | E. coli |
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |