Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22344 |
Icatibant Acetate
|
Bradykinin Receptor | GPCR/G Protein |
Icatibant acetate 是一种特异性缓激肽 B2 受体拮抗剂,其 IC50=1.07 nM,Ki=0.798 nM。 | |||
T24147 |
Hoe 140, desarg(10)-
10-Desarg-hoe 140 |
||
Hoe 140 is an effective antagonist of B1 bradykinin. | |||
T15547 |
Icatibant
艾替班特,HOE 140 |
Others | Others |
Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively). | |||
T83500 |
[Des-Arg10]-HOE I40
|
||
[Des-Arg10]-HOE 140 是一种有效的 B1 缓激肽受体拮抗剂,具备生物活性。 | |||
TP1999 |
MEN 11270
|
||
Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3); conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5). |