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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76710 Lanadelumab

Lanadelumab (SHP643) 是一种针对血浆激肽释放酶 (plasma kallikrein (pKal)) 的人源化IgG1单克隆抗体,Ki 值为 0.12 nM。Lanadelumab 抑制游离和 HMWK 结合的 pKal。Lanadelumab 具有研究遗传性血管性水肿的潜力

化合物

Lanadelumab
Cat.No: T76710
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00734 KNG1 Protein, Human, Recombinant (His)

KNG1,High Molecular Weight Kininogen,BDK,HMWK,KNG,W...

Human HEK293 Cells
Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role in blood coagulation and inflammatory response. Kininogens are inhibitors of thiol proteases. Kininogen-1 participates in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, also inhibits the thrombin- and plasmin-induced aggregation...
TMPH-01581 KRT1 Protein, Human, Recombinant (His)

Human E. coli
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. KRT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.9 kDa and the accession number is P04264.

重组蛋白

KNG1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00734
Species: Human
Expression System: HEK293 Cells
KRT1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01581
Species: Human
Expression System: E. coli
TargetMol Loading
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