Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70460 |
HM5023507
|
Others | Others |
HM5023507, an orally active dual inhibitor of δγ isoforms in immune signaling. HM5023507 inhibited PI3Kδ and PI3Kγ isoforms with greater than 100-fold selectivity against PI3Kα and PI3Kβ in recombinant enzymatic assays and in primary human immune cells with an exquisite selectivity against other targets. |