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Cat. No.	Product Name	Target	Signaling Pathways
T39990	HDAC-IN-26
	HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC 50 value of 4.7 nM.
T64261	HDAC/HSP90-IN-4
	HDAC/HSP90-IN-4 能够明显抑制 HDAC 和 HSP90 的活性，化合物20（HDACIC50= 194 nM; HSP90αIC50= 153 nM）和化合物26（(HDACIC50= 360 nM; HSP90αIC50= 77 nM) 具有较强的 HDAC 和 HSP90α抑制效果。这两种化合物都能诱导 HSP90表达并下调 HSP90客户蛋白，而 HSP90客户蛋白在调节癌细胞的生存和侵袭中发挥着重要作用。
T71420	RO314724
	RO314724 is a HDAC inhibitor. RO314724 is also a a reversible, tightly binding, MMP inhibitor with a Ki of 26 nm. Matrix metalloproteinases (MMPs) belong to the key enzymes of the proteolytic destruction of cartilage matrix during chronic rheumatic diseases. Ro314724 displayed MMP-proteoglycanase inhibitory activity both in vitro and ex vivo and proved to be not harmful to the morphology, viability and proteoglycan biosynthesis of bovine articular cartilage explants.