Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04170 |
DEFB1 Protein, Human, Recombinant (hFc)
DEFB101,defensin, β1,β Defensin <... |
Human | HEK293 Cells |
The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. On... | |||
TMPJ-00003 |
DEFB1 Protein, Human, Recombinant
Beta-Defensin 1,BD-1,HBD1 |
Human | E. coli |
β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis,... |