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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T9978 Glutathione synthesis-IN-1

Others Others
Glutathione synthesis-IN-1 (DC-1)是谷胱甘肽合成抑制剂。
T14257 Aminoethyl-SS-ethylalcohol

Others Others
Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
T37166 RCTR1

Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1It has been found in human spleen and bone marrow.2RCTR1 is produced via lipoxygenase-mediated oxidation of DHA to 7(S)-8-epoxy-17(S)-HDHA, which is conjugated to glutathione.1,2,3RCTR1 (10 nM) increases phagocytosis ofE. colior apoptotic neutrophils in isolated human monocyte-de...

化合物

Glutathione synthesis-IN-1
Cat.No: T9978
Synonym:
Target: Others
Aminoethyl-SS-ethylalcohol
Cat.No: T14257
Synonym:
Target: Others
RCTR1
Cat.No: T37166
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T35770 Cylindrospermopsin

Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...

天然产物

Cylindrospermopsin
Cat.No: T35770
Synonym:
Target:
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