Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11522 |
GYKI 52466 dihydrochloride
|
Others | Others |
GYKI 52466 dihydrochloride is orally active and non-competitive kainate- and AMPA-activated currents antagonist (IC50s: 7.5 μM and 11 μM). It is inactive against NMDA or γ-aminobutyric acid responses. It is a muscle relaxant and anticonvulsant agent and h | |||
T70062 |
Osteoprotegerin
|
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Osteoprotegerin is a soluble secreted member of the tumor necrosis factor receptor superfamily, inhibiting osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, leading to excess accumulation of bone and cartilage. | |||
T21449 |
GYKI-52466
GYKI 52,466,GYKI-5,2466,GYKI52,466 |
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GYKI-52466 is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >50 μM for AMPA-, kainate- and NMDA-induced responses, respectively) used as a Skeletal muscle relaxant, orally active anticonvulsant, neuroprotective and |