Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12038 |
Migalastat hydrochloride
GR181413A hydrochloride,Migalastat HCl,GR181413A HCl |
Others | Others |
Migalastat hydrochloride (GR181413A) 是一种可口服且具有有效和竞争性的 α-galactosidase A 抑制剂,可促进α-半乳糖苷酶A向溶酶体的运输,可用于研究法布里病。 | |||
T71481 |
Migalastat
GR181413A free base |
||
Migalastat (GR181413A free base) 是一种具有口服活性和竞争性的α-galactosidase A 抑制剂,对人α-Gal A 的IC50值为 0.04 μM。 | |||
T71479 | Kahweol oleate | ||
Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell cycle arrest and apoptosis in oral squamous cell carcinoma cells, preventing aflatoxin B1 induced DNA adduct formation, and suppressing H2O2-induced DNA damage and oxidative stress. |