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Cat. No.	Product Name	Target	Signaling Pathways
T69826	U-0126
	U0126 is a highly selective inhibitor of both MEK1 and MEK2, a type of MAPK/ERK kinase. It was found to functionally antagonize AP-1 transcriptional activity via noncompetitive inhibition of the dual specificity kinase MEK with IC50 of 72 nM for MEK1 and 58 nM for MEK2. U0126 inhibited anchorage-independent growth of Ki-ras-transformed rat fibroblasts by simultaneously blocking both extracellular signal-regulated kinase and mammalian target of rapamycin pathways.
T69827	GPA-1734 bromide
	GPA-1734 bromide is an inhibitor of basement membrane collagen synthesis and angiogenesis.