Cat. No. | Product Name | Target | Signaling Pathways |
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T62938 |
GNE-617 hydrochloride
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GNE-617 hydrochloride 是一种 NAMPT 的特异性抑制剂,能够抑制 NAMPT 活性 (IC50: 5 nM)。 | |||
T22801 |
GNE-617 hydrochloride (1362154-70-8 free base)
GNE-617 hydrochloride |
Others | Others |
GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50 |