Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62905 | GLS-1-IN-1 | ||
GLS-1-IN-1 (compound 1d) 是一种 GLS-1 抑制剂,能够抑制 Hep G2、MCF 7 和 MCF 10A 细胞。 | |||
T39544 |
IPN60090 dihydrochloride
IPN60090 dihydrochloride |
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IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers. |