Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83694 |
Gastric Inhibitory Peptide (1-42) (porcine) TFA
GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42) |
||
胃抑制肽(GIP) (1-42)是一种内源性的42氨基酸肽类肠促素激素,能诱导胰岛素分泌。该激素在肠道神经内分泌K细胞和颌下腺中表达,并在餐后释放到循环中。GIP (1-42)抑制由组胺、五肽和胰岛素引起的胃酸和胃蛋白酶分泌,增加葡萄糖诱导的胰岛素释放,并在大鼠中刺激胃排空。 | |||
T83696 |
Gastric Inhibitory Peptide 1 (3-42) (human) TFA
Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42) |
||
胃抑制肽1(GIP-1) (3-42)是肠促胰岛素激素GIP的一个肽段,同时也是GIP受体的拮抗剂。它通过血清二肽基肽酶4(DDP-4)从GIP中形成。GIP-1 (3-42) (100 nM)在减少BRIN-BD11胰腺细胞的胰岛素分泌方面起作用。在以25 nmol/kg剂量给药的ob/ob糖尿病小鼠模型中,它能增加血浆葡萄糖水平并降低血浆胰岛素水平。 | |||
T37601 |
GIP (1-30) amide, porcine TFA
|
||
GIP (1-30) amide, porcine TFA is a high-affinity full agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor, having a similar potency as the native GIP(1-42) [1]. Furthermore, GIP (1-30) amide, porcine displays weak inhibitory effects on gastric acid secretion while exhibiting potent insulin-stimulating properties. | |||
T76307 |
[Tyr0] Gastric Inhibitory Peptide (23-42), human
|
||
[Tyr0]Gastric Inhibitory Peptide(23-42), human,属于葡萄糖依赖性促胰岛素多肽(GIP)类,具有抑制胃酸分泌并促进胰岛素释放的功能。它在糖尿病和肥胖症的研究中有应用价值。 | |||
T75757 |
GIP, human TFA
|
||
GIP, human TFA 是一种42个氨基酸构成的肽类激素,促进葡萄糖依赖性胰岛素释放,同时轻度抑制胃酸分泌。该激素由肠K细胞释放,响应营养摄入。 |