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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77067 | Livmoniplimab | ||
Livmoniplimab (ABBV-151; ARGX-115) 是一种有效的人源化抗 LRRC32 (GARP)/TGFβ1 单克隆抗体。Livmoniplimab 阻断 LRRC32 介导的潜在 TGFβ1 激活。Livmoniplimab 具有癌症研究的潜力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05085 |
LRRC32 Protein, Human, Recombinant (His)
leucine rich repeat containing 32,GARP,D11S833E |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPY-06355 |
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
转化生长因子,TGF β1 & GARP Heterotrimer |
Human | HEK293 Cells |
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 108.72 kDa and the accession number is P01137. | |||
TMPJ-00364 |
LRRC32 Protein, Human, Recombinant (hFc)
D11S833E,GARPGarpin,GARP,Garp... |
Human | HEK293 Cells |
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRR... | |||
TMPY-05375 |
LRRC32 Protein, Human, Recombinant (His), Biotinylated
leucine rich repeat containing 32,D11S833E,GARP |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPY-06705 |
LRRC32 Protein, Mouse, Recombinant (His)
Garp,AI426318,leucine rich repeat containing 32,D11... |
Mouse | HEK293 Cells |
LRRC32 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.10 kDa and the accession number is G3XA59. | |||
TMPY-06703 |
LRRC32 Protein, Mouse, Recombinant (hFc)
leucine rich repeat containing 32,D11S833Eh,Garp,D7... |
Mouse | HEK293 Cells |
LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59. |