1
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77450 |
Vantictumab
OMP-18R5 |
||
Vantictumab (OMP-18R5)为全人源IgG2单克隆抗体,针对FZD1/2/5/7/8受体抑制Wnt信号通路。该抗体适用于研究治疗转移性HER2阴性乳腺癌及转移性胰腺腺癌。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01165 |
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
Fzd1,AW227548,frizzled class receptor ... |
Mouse | HEK293 Cells |
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signalin... | |||
TMPJ-00354 |
FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)
Frizzled-1,mFz1,Fzd1,Fz-... |
Mouse | HEK293 Cells |
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. |