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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T77450 Vantictumab

OMP-18R5

Vantictumab (OMP-18R5)为全人源IgG2单克隆抗体,针对FZD1/2/5/7/8受体抑制Wnt信号通路。该抗体适用于研究治疗转移性HER2阴性乳腺癌及转移性胰腺腺癌。

化合物

Vantictumab
Cat.No: T77450
Synonym: OMP-18R5
Target:
Cat. No. Product Name Species Expression System
TMPY-01165 FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)

Fzd1,AW227548,frizzled class receptor ...

Mouse HEK293 Cells
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signalin...
TMPJ-00354 FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)

Frizzled-1,mFz1,Fzd1,Fz-...

Mouse HEK293 Cells
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.

重组蛋白

FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01165
Species: Mouse
Expression System: HEK293 Cells
FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00354
Species: Mouse
Expression System: HEK293 Cells
TargetMol Loading
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