Cat. No. | Product Name | Target | Signaling Pathways |
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TP1296 |
Foxy-5 TFA(881188-51-8 free base)
Foxy-5 (TFA) |
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Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial c | |||
T75941 |
Foxy-5 TFA
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Foxy-5 TFA 是WNT5A 激动剂,是 WNT5A 的一个模拟肽,是Wnt 家族的非经典成员。Foxy-5 TFA 可在不影响β-catenin 激活的情况下触发胞浆游离钙信号传导,并可抑制上皮癌细胞的迁移和侵袭。Foxy-5 TFA 在原位小鼠模型中能有效降低 WNT5A 低表达的前列腺癌细胞的转移扩散。 |