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Cat. No. | Product Name | Target | Signaling Pathways |
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T37791 |
A-971432
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A-971432 is a sphingosine-1-phosphate receptor 5 (S1P5) agonist that is selective for S1P5 over S1P1 and S1P3 (IC50s = 0.006, 0.362, and >10 µM, respectively). It inhibits forskolin-induced cAMP production in CHO cells expressing S1P5 (EC50 = 4.1 nM). A-971432 (1 µM) increases electrical resistance of hCMEC/D3 cells in an in vitro blood-brain barrier model, indicating enhanced barrier integrity, and attenuates blood-brain barrier leakage in an R6/2 transgenic mouse model of Huntington’s ... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN4074 |
Forskolin J
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Others | Others |
Forskolin J 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4074,CAS号为 81873-08-7。 |