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Cat. No. | Product Name | Target | Signaling Pathways |
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T71483 |
Streptonigrin (racemate)
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Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer. | |||
T16440 |
Ibrutinib Racemate
PCI-32765 (Racemate) |
Others | Others |
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib. | |||
T13814 |
Pemafibrate (racemate)
K13675 (racemate) |
Others | Others |
Pemafibrate racemate is the racemate of pemafibrate | |||
T13450L |
GNE-140 racemate
GNE-140 (racemate) |
Others | Others |
GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16946 |
Streptonigrin
Bruneomycin |
Others | Others |
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD |