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Cat. No. Product Name Species Expression System
TMPY-00176 FNDC4 Protein, Human, Recombinant (mFc)

fibronectin type III domain containing 4,FRCP1<...

Human HEK293 Cells
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of FNDC4 to different immune cell types reveals strong and specific binding to macrophages and monocytes. FNDC4 treatment of bone marrow-derived macrophages in vitro results in reduced phagocytosis, increased cell survival and reduced proinflammatory chemokine expression. Hence, trea...

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FNDC4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00176
Species: Human
Expression System: HEK293 Cells
TargetMol Loading
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