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Cat. No. Product Name Target Signaling Pathways
T36807 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...

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Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
Cat.No: T36807
Synonym:
Target:
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