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Search Results for " enterobacteriaceae "

16

抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
T4017	Relebactam 瑞来巴坦,MK-7655	Antibacterial	Microbiology/Virology
	Relebactam (MK-7655) 是一种有广谱抗β内酰胺酶活性的二氮杂双环辛烷抑制剂。
T23801	WCK-4234 sodium WCK-4234,WCK4234,WCK 4234	Antibacterial	Microbiology/Virology
	WCK-4234 sodium (WCK 4234) 是一种 β-内酰胺酶抑制剂，可用于针对 MDR 感染的研究。 WCK-4234 sodium 抑制 A、C 和 D 类 β-内酰胺酶和 OXA 碳青霉烯酶。
T61037	Glycosyltransferase-IN-1	Others	Others
	Glycosyltransferase-IN-1 是一种糖基转移酶 (glycosyltransferase) 抑制剂，具有抑菌活性，抑制 MSSA、MRSA 、枯草杆菌和肠杆菌。
T1190	Cefmenoxime hydrochloride Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride,盐酸头孢甲肟	Antibacterial; Antibiotic; Antifection	Microbiology/Virology
	Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) 是一种头孢类抗生素，可通过静脉内或肌肉内给药。它对大多数常见的革兰氏阳性和革兰氏阴性微生物有活性，是一种肠杆菌科抑制剂，并且对 β-内酰胺酶的水解具有高度抗性。
T70319	ANT431
	ANT431 is a novel metallo-β-lactamase inhibitor for the treatment of carbapenem-resistant enterobacteriaceae infections
T30488	BMS 180680 BMS-180680,SQ 84,100,BMS180680
	BMS 180680 is a novel catechol-containing monolactam antibacterial active agent, which is the most effective compound against many species of Enterobacteriaceae.
T27962	Ancremonam LYS228,LYS-228,LYS 228
	LYS228 is a potent antibiotics against Carbapenem-Resistant Enterobacteriaceae (MIC90 = 2 uM/mL). LYS228 is potent in the presence of all classes of beta-lactamases.
T31036	CP 99433 CP-99433,CP99433
	CP 99433 is a new C-7 diazabicyclofluoroquinolone with a broad spectrum of activity that includes Enterobacteriaceae, Gram-positive cocci, and nonenteric Gram-negative bacilli.
T24649	Plazomicin
	Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin shows high activity against the Enterobacteriaceae.
T1190L	Cefmenoxime A-50912,A 50912,A50912,AB 50912
	Cefmenoxime is a cephalosporin antibiotic administered intravenously or intramuscularly. It is an effective inhibitor of Enterobacteriaceae and is resistant to beta-lactamase-initiated hydrolysis. It is active against most common gram-positive and gram-ne
T70076	NOSO-95C
	NOSO-95C is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.
T78507	Cefteram Cefterame,T-2525,RO 19-5247
	Cefteram (T-2525)为Cefteram pivoxil的游离酸形式，属于具有口服活性的头孢菌素酯类抗生素。该化合物对肠道致病性肠杆菌科与弧菌科细菌表现出有效的抗菌作用。
T73878	NOSO-502
	NOSO-502为一种对肠杆菌科表现出抑制效果的细菌翻译(bacterialtranslation)抑制剂，具备良好的安全性及抗菌特性。
T40662	Isepamicin Sch 21420
	Isepamicin (Sch 21420) is a potent aminoglycoside antibacterial compound with enhanced efficacy against strains harboring type I 6'-acetyltransferase. Its antibacterial spectrum encompasses Enterobacteriaceae and staphylococci, while exhibiting resistance against anaerobes, Neisseriaceae, and streptococci. Moreover, Isepamicin displays a robust concentration-dependent bactericidal effect, a prolonged post-antibiotic effect lasting several hours, and is capable of inducing adaptive resistance.
T68938	Cefmenoxime sodium
	Cefmenoxime sodium is the ssalt form of Cefmenoxime (free base), a cephalosporin antibiotic administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms. It is a potent inhibitor of Enterobacteriaceae, and is resistant to beta-lactamase-initiated hydrolysis. The drug has a high success rate against many types of infection.
T78987	SA09-Cu
	SA09-Cu是一种NDM-1的非竞争性抑制剂，具有9.6 nM的IC50。该化合物通过作用于氧化酶的Zn(II)-硫醇盐位点，能将NDM-1转化为无活性形态，从而抵御细菌细胞内的硫醇还原作用。SA09-Cu对于多种产生NDM-1的肠杆菌科碳青霉烯耐药菌株（CRE）表现出明显的抑制作用，有效恢复了美罗培南的活性，并有助于减缓碳青霉烯耐药性的进展。

化合物

Cat.No: T4017

Synonym: 瑞来巴坦,MK-7655

Target: Antibacterial

WCK-4234 sodium

Cat.No: T23801

Synonym: WCK-4234,WCK4234,WCK 4234

Target: Antibacterial

Glycosyltransferase-IN-1

Cat.No: T61037

Target: Others

Cefmenoxime hydrochloride

Cat.No: T1190

Synonym: Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride,盐酸头孢甲肟

Target: Antibacterial, Antibiotic, Antifection

Cat.No: T70319

Cat.No: T30488

Synonym: BMS-180680,SQ 84,100,BMS180680

Cat.No: T27962

Synonym: LYS228,LYS-228,LYS 228

Cat.No: T31036

Synonym: CP-99433,CP99433

Cat.No: T24649

Cat.No: T1190L

Synonym: A-50912,A 50912,A50912,AB 50912

Cat.No: T70076

Cat.No: T78507

Synonym: Cefterame,T-2525,RO 19-5247

Cat.No: T73878

Cat.No: T40662

Synonym: Sch 21420

Cefmenoxime sodium

Cat.No: T68938

Cat.No: T78987

Cat. No.	Product Name	Target	Signaling Pathways
T82755	Cefquinome	Antibiotic	Microbiology/Virology
	Cefquinome是一种头孢烯类抗生素，具有抑制多种肠杆菌科细菌的效能。

天然产物

Cat.No: T82755

Target: Antibiotic

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