Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11221 |
ERAP1-IN-1
|
Others | Others |
ERAP1-in-1 是一种内质网氨基肽酶 1 (ERAP1) 抑制剂,能竞争性地抑制 ERAP1 对代表性生物底物九聚物肽的作用。 | |||
T27160 |
DG026
DG 026,DG-026 |
||
DG026 is a IRAP inhibitor. DG026 ables to selectively downregulate IRAP-dependent cross-presentation by dendritic cells but leave ERAP1-dependent cross-presentation unaffected. | |||
T69998 | DG046 | ||
DG046 is a novel potent phosphinic pseudopeptide ERAP1 inhibitor, binding in the ERAP1 active site, being stabilized by an unusual extensive network of π-stacking interactions | |||
T63546 |
DG013A
|
||
DG013A 是次膦酸三肽模拟抑制剂,能够作用于 ERAP1 (IC50: 33 nM) 和 ERAP2 (IC50: 11 nM)。DG013A 能够用研究自身免疫性疾病和癌症。 |