Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03795 |
EIF5A2 Protein, Human, Recombinant (His)
eIF5AII,eukaryotic translation initiation factor |
Human | E. coli |
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe... |