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Cat. No. Product Name Target Signaling Pathways
T73154 EGFR-IN-70

EGFR-IN-70 是一种有效的EGFR 抑制剂,对于EGFRLR/TM/CS 和EGFRWT,其IC50值分别为 23.6 和 307.5 nM。EGFR-IN-70 具有抗增殖活性并抑制EGFR 的磷酸化。EGFR-IN-70 可用于癌症研究。
T63693 EGFR-IN-55

EGFR-IN-55 是 EGFR 的有效抑制剂,能够作用于 EGFRWT (IC50: 70 nM) 和 EGFRL858R/T790M (IC50: 3.9 nM) 。EGFR-IN-55 能够将 NCI-H1975 细胞的细胞周期阻滞在 G0/G1 期,表现出抗癌效果。
T37594 Pericosine A

Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 μM) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 μg/ml. It also reacts with organosulfur compounds in skunk spray to form stable t...

化合物

EGFR-IN-70
Cat.No: T73154
Synonym:
Target:
EGFR-IN-55
Cat.No: T63693
Synonym:
Target:
Pericosine A
Cat.No: T37594
Synonym:
Target:
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