Cat. No. | Product Name | Target | Signaling Pathways |
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T69807 |
EGFR-IN-451
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EGFR-IN-451 is an EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis. | |||
T69806 |
EGIS-8332
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EGIS-8332 is a potent and selective non-competitive AMPA receptor antagonist. EGIS-8332 inhibits AMPA/kainate ion channels and cell death. EGIS-8332 inhibited AMPA currents in rat cerebellar Purkinje cells and inhibited the AMPA- and quisqualate-induced excitotoxicity in primary cultures of telencephalon neurons (IC(50)=5.1-9.0 microM), in vitro. EGIS-8332 seems suitable for further development for the treatment of epilepsy, ischaemia and stroke based on its efficacy in a variety of experimenta... |