Cat. No. | Product Name | Target | Signaling Pathways |
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T79628 | DprE1-IN-8 | Antibiotic | Microbiology/Virology |
DprE1-IN-8是一种针对DprE1的有效抑制剂,具备抗Mtb H37Rv能力,IC50值低于0.75 μM,针对Mtb H37Rv的IC50达到6 nM,适用于结核病的研究领域。 | |||
T37880 |
OPC-167832
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OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |