Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4044 |
DprE1-IN-2
|
Antibacterial; DprE1 | Microbiology/Virology; Others |
DprE1-IN-2 是 DprE1抑制剂,IC50为 28 nM,有抗结核作用。 | |||
T37880 |
OPC-167832
|
||
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |