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Cat. No. Product Name Target Signaling Pathways
T35939 Dabigatran Acyl-β-D-Glucuronide

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.

化合物

Dabigatran Acyl-β-D-Glucuronide
Cat.No: T35939
Synonym:
Target:
TargetMol Loading
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